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This entry has 1 described isoform and 4 potential isoforms that are computationally mapped. Show all Align All.

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Basket 0. Your basket is currently empty. RAS guanyl-releasing protein 1. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence s displayed.

Select a section on the left to see content. Functions in mast cell degranulation and cytokine secretion, regulating FcERI-evoked allergic responses PubMed: May also function in differentiation of other cell types.

Proto-oncogene, which promotes T-cell lymphomagenesis when its expression is deregulated PubMed: , PubMed: Cancer Res. Activated by diacylglycerol and calcium binding, which induces a conformational change releasing the autoinhibitory state.

Regulated by DGKA. Regulated by DGKZ. Alternative name s :. Name: Rasgrp1 Synonyms: Rasgrp. UniProt annotation GO - Cellular component Plasma membrane Cell membrane By similarity ; Peripheral membrane protein By similarity Cytosol cytosol By similarity Endoplasmic reticulum Endoplasmic reticulum membrane By similarity ; Peripheral membrane protein By similarity Golgi apparatus Golgi apparatus membrane ; Peripheral membrane protein Note: Found both in the cytosol and associated with membranes.

Relocalization to the cell membrane upon activation is F-actin-dependent By similarity. Translocates to the Golgi in response to phorbol ester or nerve growth factor.

Localizes to somata and dendrites but not to axons of hippocampal pyramidal cells By similarity. By similarity. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.

Lag lymphoproliferation-autoimmunity-glomerulonephritis mice do not express Rasgrp1 and display a systemic lupus erythematosus-like phenotype.

By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.

Expressed by mature thymocytes and to a lower extent by bone marrow-derived mast cells at protein level. Detected in B-cells and keratinocytes at protein level.

Up-regulated at the double-negative to double-positive transition during thymocyte development. Down-regulated by O-tetradecanoylphorbolacetate TPA.

Interacts with F-actin. ModBase i Search The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain.

Several domains are described in this subsection. Two EF-hand domains are present. However, only EF-hand 1 and not EF-hand 2 binds calcium.

The information is filed in different subsections. Length: Mass Da : 90, It is useful for tracking sequence updates.

The algorithm is described in the ISO standard. Cebus capucinus imitator. Full view. These are stable identifiers and should be used to cite UniProtKB entries.

Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary citable accession number'.

See complete history. Do not show this banner again. One common calcium-binding motif is the EF-hand, but other calcium-binding motifs also exist.

Calcium , Metal-binding , Zinc. Reactome - a knowledgebase of biological pathways and processes More Reactome i.

This is known as the 'taxonomic identifier' or 'taxid'. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.

MGI i. Encyclopedia of Proteome Dynamics More EPD i. MaxQB i. PaxDb, a database of protein abundance averages across all three domains of life More PaxDb i.

On This Page. Name Poster. How to Pronounce Hgfdsa. Is this an accurate pronunciation? How difficult is it to pronounce Hgfdsa? Can Hgfdsa be pronounced multiple ways?

Record your pronunciation Recording. Click to stop. We noticed you have a microphone. If you know how to pronounce Hgfdsa, just click the button to record.

We'll save it, review it, and post it to help others. Recordings from children under 18 are not allowed. Back to Top. Meaning and Origin What does the name Hgfdsa mean?

Find out below. Origin and Meaning of Hgfdsa. Hgfdsa Means. Cited Source. We will review your submission shortly!

International Interest. Also see international interest. H is for hardy, can't keep you down! G is for giggle, a laugh never hurts!

F is for fancy, never just plain you! D is for dependable, on you I can rely. S is for superb, a great attitude about life.

A is for adorable, how precious. Where is the name Hgfdsa popular?

Lag lymphoproliferation-autoimmunity-glomerulonephritis mice do not express Rasgrp1 and display a systemic lupus erythematosus-like phenotype.

By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'. Expressed by mature thymocytes and to a lower extent by bone marrow-derived mast cells at protein level.

Detected in B-cells and keratinocytes at protein level. Up-regulated at the double-negative to double-positive transition during thymocyte development.

Down-regulated by O-tetradecanoylphorbolacetate TPA. Interacts with F-actin. ModBase i Search The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain.

Several domains are described in this subsection. Two EF-hand domains are present. However, only EF-hand 1 and not EF-hand 2 binds calcium.

The information is filed in different subsections. Length: Mass Da : 90, It is useful for tracking sequence updates. The algorithm is described in the ISO standard.

Cebus capucinus imitator. Full view. These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary citable accession number'.

See complete history. Do not show this banner again. One common calcium-binding motif is the EF-hand, but other calcium-binding motifs also exist.

Calcium , Metal-binding , Zinc. Reactome - a knowledgebase of biological pathways and processes More Reactome i.

This is known as the 'taxonomic identifier' or 'taxid'. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.

MGI i. Encyclopedia of Proteome Dynamics More EPD i. MaxQB i. PaxDb, a database of protein abundance averages across all three domains of life More PaxDb i.

PRIDE i. PhosphoSitePlus i. Bgee i. ExpressionAtlas i. Genevisible search portal to normalized and curated expression data from Genevestigator More Genevisible i.

RNAct i. SMR i. Database of comparative protein structure models More ModBase i. Suppress the PT region-mediated translocation to plasma membrane.

Ensembl GeneTree More GeneTree i. InParanoid i. Database of Orthologous Groups More OrthoDB i. Database for complete collections of gene phylogenies More PhylomeDB i.

TreeFam database of animal gene trees More TreeFam i. Conserved Domains Database More CDD i. Gene3D i. Integrated resource of protein families, domains and functional sites More Is this an accurate pronunciation?

How difficult is it to pronounce Hgfdsa? Can Hgfdsa be pronounced multiple ways? Record your pronunciation Recording. Click to stop.

We noticed you have a microphone. If you know how to pronounce Hgfdsa, just click the button to record. We'll save it, review it, and post it to help others.

Recordings from children under 18 are not allowed. Back to Top. Meaning and Origin What does the name Hgfdsa mean?

Find out below. Origin and Meaning of Hgfdsa. Hgfdsa Means. Cited Source. We will review your submission shortly!

International Interest. Also see international interest. H is for hardy, can't keep you down! G is for giggle, a laugh never hurts! F is for fancy, never just plain you!

D is for dependable, on you I can rely. S is for superb, a great attitude about life. A is for adorable, how precious.

Where is the name Hgfdsa popular? International Interest for Hgfdsa Interest is based how many people viewed this name from each country and is scaled based on the total views by each country so that large countries do not always show the most interest.

Fun Facts about the name Hgfdsa How unique is the name Hgfdsa? Out of 6,, records in the U.

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